Stilnoct (Zolpidem Tartrate) – Sedative-Hypnotic for Short-Term Insomnia (Rx, Controlled)
Stilnoct (zolpidem tartrate) is a non-benzodiazepine sedative-hypnotic used for the short-term treatment of insomnia, particularly for difficulty falling asleep.
It works by selectively binding to the GABA-A receptor complex (omega-1 subtype), enhancing inhibitory neurotransmission in the brain. This produces sedation, reduced sleep latency, and improved sleep onset, without being a classical benzodiazepine.
Because of its rapid onset and short duration, it is typically used for sleep initiation insomnia rather than long-term sleep disorders.
Key Details
- Active Ingredient: Zolpidem tartrate
- Drug Class: Non-benzodiazepine hypnotic (Z-drug)
- Indication: Short-term insomnia treatment
- Mechanism of Action: GABA-A receptor modulation → CNS sedation
- Prescription Status: Controlled prescription medicine
Specifications
- Dosage Forms: Oral tablets
- Common Strengths: 5 mg, 10 mg
- Administration: Oral, immediately before bedtime
- Onset of Action: ~15–30 minutes
- Duration of Action: ~6–8 hours
- Half-Life: ~2–3 hours
- Metabolism: Hepatic (CYP3A4)
- Excretion: Renal
- Storage: Room temperature
Dosage & Administration
- Typical dose: 5–10 mg once nightly
- Must be taken only when full sleep time (7–8 hours) is available
- Should be used for the shortest possible duration
- Dose adjustments may be required for elderly or sensitive patients
- Do not take with or immediately after a heavy meal (delays onset)
Compatibility / Suitable Use
- Patients with short-term insomnia or sleep-onset difficulty
- Individuals experiencing temporary sleep disruption (stress, travel, schedule changes)
- Not intended for long-term chronic insomnia treatment
- Requires medical supervision
Contraindications
- Severe respiratory insufficiency
- Sleep apnea syndrome
- Severe hepatic impairment
- Known hypersensitivity to zolpidem
- History of complex sleep behaviors with zolpidem
Why Choose Stilnoct?
Stilnoct (zolpidem) is a fast-acting sleep medication designed to help patients fall asleep quickly and improve sleep onset in short-term insomnia. It is effective when used correctly but must be limited to short durations due to dependence and safety risks.